KBP-2035 is a small molecule inhibitor of the EphA2 receptor, a protein that has been implicated in the growth and spread of cancer cells. It has been shown to effectively block EphA2 signaling and inhibit tumor growth in various cancer models, including breast, lung, and pancreatic cancers.
1363382-77-7
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Basic information
- Product Name: KBP-2035
- Synonyms: KBP-2035;methyl 5,6-dihydroxypyridine-3-carboxylate;Methyl 5,6-dihydroxynicotinate
- CAS NO:1363382-77-7
- Molecular Formula: C7H7NO4
- Molecular Weight: 169.13478
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1363382-77-7.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: 2-8°C
- Solubility: N/A
- CAS DataBase Reference: KBP-2035(CAS DataBase Reference)
- NIST Chemistry Reference: KBP-2035(1363382-77-7)
- EPA Substance Registry System: KBP-2035(1363382-77-7)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1363382-77-7(Hazardous Substances Data)
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1363382-77-7 Usage
Uses
Used in Oncology:KBP-2035 is used as an anticancer agent for its ability to effectively block EphA2 signaling and inhibit tumor growth in various cancer models, including breast, lung, and pancreatic cancers.
Used in Drug Resistance:
KBP-2035 is used to overcome drug resistance in cancer cells, enhancing the efficacy of standard chemotherapy and making it a promising candidate for further clinical development.
Used in Cancer Research:
KBP-2035 is used in preclinical studies to investigate its potential as a therapeutic agent for the treatment of various cancer types, given its ability to block EphA2 signaling and inhibit tumor growth.
Check Digit Verification of cas no
The CAS Registry Mumber 1363382-77-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,6,3,3,8 and 2 respectively; the second part has 2 digits, 7 and 7 respectively.Calculate Digit Verification of CAS Registry Number 1363382-77:
(9*1)+(8*3)+(7*6)+(6*3)+(5*3)+(4*8)+(3*2)+(2*7)+(1*7)=167
167 % 10 = 7
So 1363382-77-7 is a valid CAS Registry Number.
1363382-77-7Upstream product
1363382-77-7Downstream Products
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KBP-2035
