136339-28-1Relevant academic research and scientific papers
Stereoselective synthesis and reactivity of dienyl zirconocene derivatives
Chinkov, Nicka,Majumdar, Swapan,Marek, Ilan
, p. 2411 - 2417 (2007/10/03)
Stereoselective dienyl zirconocene derivatives have been prepared via a tandem allylic C-H bond activation isomerization-elimination reaction. These reagents can be either trapped directly with electrophiles or transmetalated to copper to participate in s
Stereoselective Preparation of Dienyl Zirconocene Complexes via a Tandem Allylic C-H Bond Activation-Elimination Sequence
Chinkov, Nicka,Majumdar, Swapan,Marek, Ilan
, p. 13258 - 13264 (2007/10/03)
Several dienyl zirconocene derivatives were easily prepared, as unique geometrical isomers, from simple non-conjugated unsaturated enol ethers with (1-butene)ZrCp2 complexes. This new methodology is based on a tandem allylic C-H bond activation-elimination sequence and the mechanism has been mapped out by deuterium labeling experiments. The stereochemical outcome of this process was determined by addition of several electrophiles. Moreover, when the organometallic derivative is vinylic as well as allylic such as in 44-47Zr, an unexpected reversal of the stereochemistry has been found during the zirconium to copper transmetalation step.
New approach to the stereoselective synthesis of metalated dienes via an isomerization-elimination sequence
Chinkov, Nicka,Majumdar, Swapan,Marek, Ilan
, p. 10282 - 10283 (2007/10/03)
Treatment of Cp2ZrBu2 with enol ether containing a remote double bond lead to conjugated metalated diene as single isomer via a tandem isomerization-elimination sequence. 2-Arylsulfonyl 1,3-dienes can also be used as a source of dienyl zirconocene derivatives, and the stereochemistry of the diene is dependent on the transmetalation reaction. Copyright
Radical cyclizations of functionalized allenes
Crandall,Ayers
, p. 3659 - 3662 (2007/10/02)
Substitution of P(O)Ph2, SOPh, and SO2Ph on an allene facilitates intramolecular radical addition to the central allene carbon to provide good yields of five-, six-, and seven-membered carbocycles.
