1363396-85-3Relevant articles and documents
An efficient synthesis of (R)-3-aminothiolane
Pan, Xianhua,Tao, Xiaohu,Ruan, Libo,Li, Yiming,Ou, Wenhua,Liu, Feng
, p. 729 - 730 (2011)
An efficient synthesis of (R)-3-aminothiolane is described based on a one-pot tandem hydroxyl activation-intramolecular cyclisation of Ts-protected-D-methioninol in the presence of methanesulfonyl chloride/pyridine. Removal of the tosyl group then gave (R)-3-aminothiolane in good yield. (R)-3-Aminothiolane derivatives are important building blocks for the synthesis of biologically active compounds.