136340-87-9

Basic information

• Product Name: N-(2-methylphenyl)thiophene-2-carboxamide
• Synonyms: N-(2-methylphenyl)thiophene-2-carboxamide
• CAS NO: 136340-87-9
• Molecular Formula: C₁₂H₁₁NOS
• Molecular Weight: 217.28684
• Mol File: 136340-87-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(2-methylphenyl)thiophene-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-methylphenyl)thiophene-2-carboxamide(136340-87-9)
• EPA Substance Registry System: N-(2-methylphenyl)thiophene-2-carboxamide(136340-87-9)

Safety Data

• Hazardous Substances Data: 136340-87-9(Hazardous Substances Data)

Upstream product

• 5271-67-0 2-Thiophenecarbonyl chloride 
• 95-53-4 o-toluidine 
• 527-72-0 2-thiophenylcarboxylic acid 

Downstream Products

• 20851-07-4 2,3,5-triphenylthiophene 

Relevant articles and documents

Palladium-Catalyzed Picolinamide-Directed Benzylic C(sp3)?H Chalcogenation with Diaryl Disulfides and Diphenyl Diselenide

The first palladium-catalyzed direct benzylic C(sp3)?H chalcogenation with diaryl disulfides and diphenyl diselenide has been established. The coupling reaction proceeds between the thioether radical and palladiumcycle intermediate. Picolinamide serves as an excellent directing group for the C?H activation of benzylic C(sp3)?H and can be easily removed. The current protocol exhibits a relatively broad substrate scope and high functional group compatibility. A mechanistic study indicates that palladium(IV) intermediate is probably formed during the course of the reaction. (Figure presented.).