136340-94-8

Basic information

• Product Name: 2-Thiophenecarboxamide,N-(2-chlorophenyl)-
• Synonyms: 2-Thiophenecarboxamide,N-(2-chlorophenyl)-;N-(2-Chlorophenyl)thiophene-2-carboxaMide
• CAS NO: 136340-94-8
• Molecular Formula: C₁₁H₈ClNOS
• Molecular Weight: 237.70532
• Mol File: 136340-94-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Thiophenecarboxamide,N-(2-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Thiophenecarboxamide,N-(2-chlorophenyl)-(136340-94-8)
• EPA Substance Registry System: 2-Thiophenecarboxamide,N-(2-chlorophenyl)-(136340-94-8)

Safety Data

• Hazardous Substances Data: 136340-94-8(Hazardous Substances Data)

Upstream product

• 5813-89-8 2-thiophenylcarboxamide 
• 615-41-8 2-iodochlorobenzene 
• 5271-67-0 2-Thiophenecarbonyl chloride 
• 95-51-2 o-chloroaniline 
• 527-72-0 2-thiophenylcarboxylic acid 

Relevant articles and documents

Potassium Carbonate Promoted C-N Coupling Reaction between Benzamides and Aryl Iodides

A practical and efficient method for N-arylation of benz-amides promoted by potassium carbonate in the presence of DMEDA was developed. The reaction was carried out without addition of any transition-metal catalyst to afford a variety of N-arylated products in moderate to good yields (up to 97%).

ELCTRON IMPACT MASS SPECTRA OF SOME 2',3'-, AND 4'-SUBSTITUTED THIOPHENE-2- AND 3-CARBOXANILIDES

The electron impact mass spectra (EI/MS) of 2- and 3-carboxanilides are dominated by the peak due to the corresponding thenoyl cations formed by cleavage of the C-N amide bond.This reaction is not affected by the polar effect of the substituents present in the phenyl ring.Most of the 2'-substituted derivatives undergo a cyclisation reaction with ejection of the substituent.In addition, for 2'-methyl and 2'-ethyl derivatives of both series of thiophene anilides a cryptic "ortho"-effect was suggested as responsible of the charge retention in the aniline moiety.