136346-15-1Relevant academic research and scientific papers
Anticoagulant contrast media
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Page/Page column 13-14, (2010/02/15)
The present invention provides novel anticoagulant contrast agents, which comprise an organic scaffolding moiety, an organic anticoagulant moiety, and an imaging moiety. The invention also provides anticoagulant contrast media and methods of visualizing internal structures utilizing the novel anticoagulant contrast agents and anticoagulant contrast media.
Nonionic X-ray contrast agents, compositions and methods
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, (2008/06/13)
Triiodinated isophthalamide derivatives, useful as X-ray contrast agents, having at least one amide group derived from the amino-alcohol, 3-(N-2-hydroxyethyl)amino-1,2-propanediol, which provides high water solubility and low mammalian toxicity, and methods of preparing them. Methods of preparing 3-(N-2-hydroxyethyl)amino-1,2-propanediol are provided.
Dicarboxylic acid-bis(3,5-dicarbamoyl-2,4,6-triiodoanilides) and x-ray contrast media containing them
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, (2008/06/13)
Dicarboxylic acid bis-(3,5-dicarbomoyl-2,4,6-triiodoanilides) of general formula I STR1 wherein the amide radicals --CONR1 R2 and --CONR3 R4 are different from one another and R1 is a hydrogen, a lower alkyl radical or R2, R2 is a straight-chain or branched-chain monohydroxy or polyhydroxy alkyl radical, R3 is hydrogen, a lower alkyl radical or R4, R4 is a straight-chain or branched-chain monohydroxy or polyhydroxy alkyl radical, R5 is hydrogen, a lower alkyl radical or a monohydroxy or polyhydroxy alkyl radical, X is a straight-chain or branched-chain alkylene with 1 to 6 carbon atoms, which optionally can be substituted by 1 to 6 hydroxy or alkoxy groups or interrupted by one or more oxygen atoms, possess good pharmacological and physicochemical properties rendering them outstandingly suitable as radiopaque substances in X-ray contrast media for use in all fields of application for X-ray contrast media.
