1363533-12-3Relevant articles and documents
Mycobacterium tuberculosis lysine-?-aminotransferase a potential target in dormancy: Benzothiazole based inhibitors
Reshma, Rudraraju Srilakshmi,Jeankumar, Variam Ullas,Kapoor, Nidhi,Saxena, Shalini,Bobesh, Karyakulam Andrews,Vachaspathy, Astakala Rishi,Kolattukudy, Pappachan E.,Sriram, Dharmarajan
, p. 2761 - 2771 (2017)
MTB lysine-?-aminotransferase (LAT) was found to play a crucial role in persistence and antibiotic tolerance. LAT serves as a potential target in the management of latent tuberculosis. In present work we attempted to derivatize the benzothiazole lead iden
(E)-2-(1,3-Benzothiazol-2-yl)-3-(4-fluorophenyl)acrylonitrile: A chain of π-stacked hydrogen-bonded rings
Trilleras, Jorge,Velásquez, Kelly,Cobo, Justo,Glidewell, Christopher
, p. 671 - 673 (2013)
The title compound, C16H9FN2S, crystallizes as a nonmerohedral twin with twin rotation about the reciprocal-lattice vector [101]*. The molecules are nearly planar and the dihedral angle between the planes of the two aryl r
Microwave-Assisted synthesis under solvent-free conditions of (E)-2-(Benzo[d]thiazol-2-yl)-3-arylacrylonitriles
Trilleras, Jorge E.,Velasquez, Kelly J.,Pacheco, Dency J.,Quiroga, Jairo,Orti?z, Alejandro
experimental part, p. 2396 - 2402 (2012/03/08)
A series of (E)-2-(benzo[d]thiazol-2-yl)-3-arylacrylonitriles was synthesized by microwave assisted Knoevenagel condensation under solvent-free conditions from the corresponding 2-(benzo[d]thiazol-2-yl)acetonitrile and aromatic aldehydes with electrondona