1363597-85-6Relevant academic research and scientific papers
Palladium and copper cocatalyzed tandem N-H/C-H bond functionalization: Synthesis of CF3-containing indolo- and pyrrolo[2,1-a ]isoquinolines
Sun, Lei-Lei,Liao, Zhi-Yong,Tang, Ri-Yuan,Deng, Chen-Liang,Zhang, Xing-Guo
experimental part, p. 2850 - 2856 (2012/05/07)
A palladium- and copper-catalyzed tandem N-H/C-H bond functionalization reaction of ortho-(2-chlorovinyl)bromobenzenes with indoles and pyrroles has been developed. A variety of CF3-containing indolo- and pyrrolo[2,1-a]isoquinolines were prepared in moderate to good yields via the cyclization of 1-bromo-2-(2-chloro-3,3,3-trifluoroprop-1-enyl)benzenes with indoles and pyrroles.
