1363662-62-7

Upstream product

• 3731-51-9 2-(Aminomethyl)pyridine 
• 86771-81-5 N-(2-bromoethyl)-2-methoxy-4-nitroaniline 
• 66095-81-6 N-(2-hydroxyethyl)-2-methoxy-4-nitroaniline 
• 97-52-9 2-methoxy-4-nitrophenylamine 

Downstream Products

• 1363667-64-4 C₂₅H₃₆N₄O₅ 
• 1311164-62-1 C₃₀H₃₃N₅O₃ 
• 1363666-45-8 C₂₅H₃₄N₄O₇ 

Relevant academic research and scientific papers

Two-photon probes for Zn2+ ions with various dissociation constants. Detection of Zn2+ ions in live cells and tissues by two-photon microscopy

A series of Zn2+-selective two-photon fluorescent probes (AZnM1-AZnN) that had a wide range of dissociation constants (Kd TP=8 nm-12 νM) were synthesized. These probes showed appreciable water solubility (>3 νM), cell permeability, high photostability, pH insensitivity at pH>7, significant two-photon action cross-sections (86-110 GM) upon complexation with Zn2+, and can detect the Zn2+ ions in HeLa cells and in living tissue slices of rat hippocampal at a depth of >80 νm without mistargeting and photobleaching problems. These probes can potentially find application in the detection of various amounts of Zn 2+ ions in live cells and intact tissues. A-tissue a-tissue, we all fall down: A series of Zn2+-ion selective two-photon fluorescent probes with a wide range of dissociation constants (KdTP=8 nM-12 νM) were developed to be able to detect the Zn2+ ions in live cells and intact tissues at a depth of>80 νm without the drawbacks of mistargeting and photobleaching.