1363680-69-6Relevant academic research and scientific papers
Synthesis, characterization and biological activity of ferrocene-based Schiff base ligands and their metal (II) complexes
Liu, Yu-Ting,Lian, Gui-Dan,Yin, Da-Wei,Su, Bao-Jun
, p. 131 - 137 (2013)
Metal (II) complexes derived from S-benzyl-N-(1-ferrocenyl-3-(4- methylbenzene)acrylketone) dithiocarbazate; HL1, S-benzyl-N-(1- ferrocenyl-3-(4-chlorobenzene)acrylketone)dithiocarbazate; HL2, all the compounds were characterized using various spectroscopic techniques. The molar conductance data revealed that the chelates were non-electrolytes. IR spectra showed that the Schiff bases were coordinated to the metal ions in a bidentate manner with N, S donor sites. The ligands and their metal complexes have been screened for in vitro antibacterial, antifungal properties. The result of these studies have revealed that zinc (II) complexes 6 and 13 of both the ligands and copper (II) complexes 9 of the HL2 were observed to be the most active against all bacterial strains, antifungal activity was overall enhanced after complexation of the ligands.
Solvent-free synthesis, characterization, biological activity of schiff bases and their metal (II) complexes derived from ferrocenyl chalcone
Dang, Yang,Li, Jie,Liu, Yuting,Sun, Jiaxi,Yang, Lan,Yang, Lisha,Yin, Dawei,Zou, Qian
, (2019/08/27)
A novel efficient method for the synthesis of ferrocenyl chalcone Schiff bases and their metal (II) complexes has been developed. Schiff bases were synthesized with TsOH (p-toluenesulfonic acid) as catalyst and complexed with metal (II) salts (Zn (II), Pb (II), Cd (II), Ni (II)). The compounds were characterized by various spectroscopic techniques and elemental analysis. The thermal stability of the complexes was performed by thermogravimetric analysis (TGA). In addition, The ligands and their metal complexes have been screened in vitro antibacterial (S. aureus, Streptococcus, Actinomycete, E. coli and P. aeruginosa), antifungal properties (C. albicans, A. fumigatus, A. niger, A. flavus, S. cerevisiae). The results revealed that Zn (II) complexes (H1, H5, H9) were the most active against all bacterial and fungal strains.
