136431-94-2 Usage
Uses
Used in Pharmaceutical Industry:
7-[(Hydroxy-2-thienyl-3-thienylacetyl)oxy]-9,9-diMethyl-3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide is used as an impurity in the synthesis of Tiotropium Bromide for its role as a muscarinic receptor antagonist. The application reason is that Tiotropium Bromide is a bronchodilator, which helps in treating conditions like chronic obstructive pulmonary disease (COPD) and asthma by relaxing the muscles in the airways and improving breathing capacity.
In the synthesis process, it is crucial to monitor and control the presence of this impurity to ensure the safety, efficacy, and quality of the final product, Tiotropium Bromide. The management of impurities is essential in the pharmaceutical industry to maintain the desired therapeutic effects and minimize potential side effects or adverse reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 136431-94-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,4,3 and 1 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 136431-94:
(8*1)+(7*3)+(6*6)+(5*4)+(4*3)+(3*1)+(2*9)+(1*4)=122
122 % 10 = 2
So 136431-94-2 is a valid CAS Registry Number.
136431-94-2Relevant academic research and scientific papers
Method for the Production of 1,3-Dioxolane-2-Ones and Carboxylic Acid Esters by Means of Transacylation in Basic Reaction Conditions
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Page/Page column 11, (2010/12/29)
The invention relates to a method for producing 1,3-dioxolane-2-ones of general formula (3) in basic reaction conditions by reesterifying the respective ester of general formula (1) in which R1 to R5 have the meanings indicated in the claims and the descr
