136465-66-2Relevant academic research and scientific papers
N-PHENYL-N,N"-GUANIDINEDICARBOXYLIC ACID ESTERS. SYNTHESIS, ANTHELMINTIC AND PESTICIDAL EFFECTS
Palat, Karel,Celadnik, Milan,Danek, Jaroslav,Varkonda, Stefan
, p. 1127 - 1133 (2007/10/02)
Substituted phenylammonium chlorides react with cyanamide to give the corresponding phenylguanidines which on treatment with chloroformate esters give N-subst.phenyl-N,N''-guanidinedicarboxylic acid esters.All substances prepared have been tested for their anthelmintic activity against the model helminths Nippostrongylus brasiliensis and Hymenolepis nana var. fraterna.The most significant activity has been found with diethyl N-(4-nitrophenyl)-N,N''-guanidinedicarboxylate.In pesticidal screening the compounds have shown fungicidal activity and particularly ovicidal activity against Tetranychus urticae which activity is increased with the compounds having a nitro group in the benzene ring.
