1364663-18-2Relevant academic research and scientific papers
Inhibition of hepatitis C virus NS5B polymerase by S-trityl-l-cysteine derivatives
Nichols, Daniel B.,Fournet, Guy,Gurukumar,Basu, Amartya,Lee, Jin-Ching,Sakamoto, Naoya,Kozielski, Frank,Musmuca, Ira,Joseph, Beno?t,Ragno, Rino,Kaushik-Basu, Neerja
experimental part, p. 191 - 199 (2012/03/27)
Structure-based studies led to the identification of a constrained derivative of S-trityl-l-cysteine (STLC) scaffold as a candidate inhibitor of hepatitis C virus (HCV) NS5B polymerase. A panel of STLC derivatives were synthesized and investigated for the
