1364685-04-0

Basic information

• Product Name: ethyl 2-(bromomethyl)-2-(4-bromophenyl)-4-ethoxy-5-oxo-2,5-dihydrofuran-3-carboxylate
• Synonyms: ethyl 2-(bromomethyl)-2-(4-bromophenyl)-4-ethoxy-5-oxo-2,5-dihydrofuran-3-carboxylate
• CAS NO: 1364685-04-0
• Molecular Weight: 448.108
• Mol File: 1364685-04-0.mol

Chemical Properties

• CAS DataBase Reference: ethyl 2-(bromomethyl)-2-(4-bromophenyl)-4-ethoxy-5-oxo-2,5-dihydrofuran-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(bromomethyl)-2-(4-bromophenyl)-4-ethoxy-5-oxo-2,5-dihydrofuran-3-carboxylate(1364685-04-0)
• EPA Substance Registry System: ethyl 2-(bromomethyl)-2-(4-bromophenyl)-4-ethoxy-5-oxo-2,5-dihydrofuran-3-carboxylate(1364685-04-0)

Safety Data

• Hazardous Substances Data: 1364685-04-0(Hazardous Substances Data)

Upstream product

• 99-73-0 para-bromophenacyl bromide 
• 762-21-0 acetylenedicarboxylic acid diethyl ester 

Relevant articles and documents

Efficient one-pot synthesis of alkyl 2-(bromomethyl)-2-(4-aryl)-4-alkoxy-5- oxo-2,5-dihydrofuran-3-carboxylate

One-pot, three-component reaction of different phenacyl bromides and dialkylacetylenedicarboxilates was carried out with triphenylphosphine and functionalized oxodihydrofuran derivatives in excellent yields. Copyright Taylor & Francis Group, LLC.

Synthesis of halogenated α,β-unsaturated γ-butyrolactone derivatives by triphenylphosphine-catalyzed cyclization of α-halogeno ketones with dialkyl acetylenedicarboxylates (=dialkyl but-2-ynedioates)

A Ph3P-catalyzed cyclization of α-halogeno ketones 2 with dialkyl acetylenedicarboxylates (=dialkyl but-2-ynedioates) 3 produced halogenated α,β-unsaturated γ-butyrolactone derivatives 4 in good yields (Scheme 1, Table). The presence of electro