136472-76-9Relevant academic research and scientific papers
SYNTHESIS OF NOVEL 5-MERCAPTO-s-TRIAZOLO-as-TRIAZINOINDOLES AND THEIR MANNICH BASES
Holla, B. Shivarama,Udupa, K. Venkatramana
, p. 1081 - 1088 (2007/10/02)
Reaction of as-triazinoindol-3-ylhydrazines with carbon disulphide in the presence of methanolic potassium hydroxide gave the title compounds through angular cyclization.On subjecting the title compounds to Mannich reaction, the NH of the triazole ring underwent aminomethylation reaction.This is further confirmed by chemical routes and by recording the uv spectra of linearly and angularly cyclized products.Structures of all the newly synthesized compounds are established on the basis of elemental analysis, 1H nmr and mass spectral data.Few selected compounds are screened for their antiviral and antibacterial properties.
