1364782-99-9

Basic information

• Product Name: (2S)-tert-butyl 2-methyl-2-phenylpiperidine-1-carboxylate
• Synonyms: (2S)-tert-butyl 2-methyl-2-phenylpiperidine-1-carboxylate
• CAS NO: 1364782-99-9
• Molecular Weight: 275.391
• Mol File: 1364782-99-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S)-tert-butyl 2-methyl-2-phenylpiperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-tert-butyl 2-methyl-2-phenylpiperidine-1-carboxylate(1364782-99-9)
• EPA Substance Registry System: (2S)-tert-butyl 2-methyl-2-phenylpiperidine-1-carboxylate(1364782-99-9)

Safety Data

• Hazardous Substances Data: 1364782-99-9(Hazardous Substances Data)

Upstream product

• 154874-89-2 tert-butyl 2-phenylipiperidine-1-carboxylate 
• 74-88-4 methyl iodide 
• 591-51-5 phenyllithium 
• 3466-80-6 2-phenylpiperidine 
• 5414-21-1 5-bromopentan-1-nitrile 
• 57050-07-4 2-phenyl-3,4,5,6-tetrahydropyridine 

Downstream Products

• 1364783-04-9 C₁₂H₁₇N 

Relevant articles and documents

Synthesis and kinetic resolution of N-Boc-2-arylpiperidines

The chiral base n-BuLi/(-)-sparteine or n-BuLi/(+)-sparteine surrogate promotes kinetic resolution of N-Boc-2-arylpiperidines by asymmetric deprotonation. The enantioenriched starting material was recovered with yields 39-48% and ers up to 97:3. On lithiation then electrophilic quench, 2,2-disubstituted piperidines were obtained with excellent yields and enantioselectivities.