136480-14-3Relevant academic research and scientific papers
Photo-induced Molecular Transformations, Part 123. One-Step Synthesis of 1H-Benzindole-4,9-diones by a New Regioselective Photoaddition of 2-Amino-1,4-naphthoquinone with Various Alkenes and Its Application to the One-Step Synthesis of Kinamycin Skeleton
Kobayashi, Kazuhiro,Takeuchi, Hiroyasu,Seko, Shinzo,Suginome, Hiroshi
, p. 1091 - 1094 (2007/10/02)
2,3-Dihydro-1H-benzindole-4,9-diones are formed in one-step in 45-82percent yields by an unprecedented -type regioselective photoaddition of 2-amino-1,4-naphthoquinone with various electron-rich alkenes and the adducts derived from aminonaphthoquinone with vinyl ethers and vinyl acetate to give 1H-benzindole-4,9-diones including a benzindole-dione with a kinamycin skeleton in 33-72percent yields.A probable pathway leading to the formation of the dihydroindole-dione involving air oxidation of an intermediary hydroquinone is proposed.
