1364822-52-5Relevant academic research and scientific papers
Direct amination of γ-Halo-β-ketoesters with anilines
Zhang, Yinan,Silverman, Richard B.
experimental part, p. 3462 - 3467 (2012/05/20)
The direct amination of α-haloacetoacetates with anilines is described. Compared to existing methods, this simple protocol provides an attractive strategy to prepare diverse γ-anilino-β-ketoesters in one step. Good to excellent yields of the amination products were obtained under robust conditions, providing versatile and useful scaffolds.
