136484-05-4

Basic information

• Product Name: 2HCl*H-His(Dnp)-LeuΨ(CH2NH)Met-NH2
• CAS NO: 136484-05-4
• Molecular Weight: 623.561
• Mol File: 136484-05-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2HCl*H-His(Dnp)-LeuΨ(CH2NH)Met-NH2(CAS DataBase Reference)
• NIST Chemistry Reference: 2HCl*H-His(Dnp)-LeuΨ(CH2NH)Met-NH2(136484-05-4)
• EPA Substance Registry System: 2HCl*H-His(Dnp)-LeuΨ(CH2NH)Met-NH2(136484-05-4)

Safety Data

• Hazardous Substances Data: 136484-05-4(Hazardous Substances Data)

Upstream product

• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 4510-08-1 L-methioninamide 
• 2280-68-4 N-tert-butoxycarbonyl-L-leucyl-L-methioninamide 
• 58521-45-2 tert-butoxycarbonyl-L-leucinal 
• 87694-50-6 N-(tert-butoxycarbonyl)-L-leucine-N'-methoxy-N'-methylamide 
• 2131-00-2 2HCl*H-LeuΨ(CH2NH)Met-NH2 

Relevant articles and documents

Bombesin receptor antagonists. 5 new irreversible alkylating analogues

New alkylating bombesin analogues were synthesized in order to increase their solubility and stability in aqueous solutions. The best compromise between these parameters and the biological properties (receptor binding and antagonistic activity) was achieved with 4-[bis(2-chloro-ethylamino)]benzoyl derivatives of the BN (7-14) octapeptide carrying a (13-14) reduced peptide bond independently of the presence of a His12 residue, either free or protected.