1364953-41-2Relevant academic research and scientific papers
Rh-catalyzed intramolecular sp2 C-H bond difluoromethylenation
Li, Yajun,Zhu, Jiangtao,Xie, Haibo,Li, Shan,Peng, Dongjie,Li, Zhengke,Wu, Yongming,Gong, Yuefa
supporting information; experimental part, p. 3136 - 3138 (2012/05/04)
A new Rh-catalyzed intramolecular coupling reaction of a CF2Br group with a 2-aryl of indole or pyrrole via C-H bond activation is presented. This reaction represents a new way of incorporating difluoromethylene groups into organic compounds. Preliminary mechanistic studies suggest that this reaction might not occur via a conventional free radical pathway. The Royal Society of Chemistry 2012.
