136498-54-9

Upstream product

• 17253-10-0 2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetonitrile 
• 608-25-3 2-methylbenzene-1,3-diol 

Downstream Products

• 202914-32-7 3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-7-hydroxy-8-methyl-chromen-4-one 
• 136498-56-1 2-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-1-(2-hydroxy-4-methoxy-3-methyl-phenyl)-ethanone 

Relevant academic research and scientific papers

Synthetic and modified isoflavonoids XIX. Synthesis of 8-methyl-substituted analogs of pseudobaptigenin

New 8-methyl-substituted chromones with 1,4-benzodioxane and 1,5-benzodioxepane nuclei in position 3 have been synthesized. Their structures have been confirmed by chemical transformations and PMR spectra.

PMR SPECTRA AND CONFORMATIONS OF BENZODIOXANE AND BENZODIOXEPAN DERIVATIVES OF FLAVANONE AND ISOFLAVANONE

PMR spectra were obtained for benzodioxane and benzodioxepan derivatives of chromanone.The heterocyclic substituent in 2-substituted chromanones (flavanone analogs) has equatorial orientation, while the heterocyclic substituent in 3-substituted chromanones (isoflavanone analogs) has axial orientation.These conclusions are based on analysis of the coupling constans, aromatic solvent-induced shifts, and shifts induced by lanthanide shift reagents.