136507-24-9

Upstream product

• 136334-41-3 (+/-)-2R^*,11bS^*-3'-(4-Fluorophenyl)-4'-imino-9,10-dimethoxy-1,3,4,6,7,11b-hexahydrospiroquinolizin-2,5'-imidazolidin>-2'-one 
• 133308-66-4 (+/-)-2R^*,11bS^*-N-(2-Cyano-9,10-dimethoxy-1,3,4,6,7,11b-hexahydrobenzoquinolizin-2-yl)-N'-(4-fluorophenyl)urea 
• 133308-74-4 2-Amino-9,10-dimethoxy-1,3,4,6,7,11b-hexahydrobenzoquinolizine-2-carbonitrile 
• 1195-45-5 para-fluorophenyl isocyanate 

Relevant academic research and scientific papers

Synthesis of 1'-Substituted and 1',3'-Disubstituted (+/-)-2R*,11bS*-9,10-Dimethoxy-1,3,4,6,7,11b-Hexahydrospiroquinolizin-2,5'-imidazolidine>-2',4'-diones

The results of the reaction between (+/-)-2R*,11bS*-2-alkyl(aryl)amino-1,3,4,6,7,11b-hexahydrobenzoquinolizine-2-carbonitriles 2 and isocyanates under a variety of experimental conditions are discussed.The ureides 3 and iminohydantoins 4 thus obtained were used to prepare N3-monosubstituted and N1,N3-disubstituted derivatives of the (+/-)-2R*,11bS*-9,10-dimethoxy-1,3,4,6,7,11b-hexahydrospiroquinolizin-2,5'-imidazolidine>-2',4'-dione system 1.The stereochemistry of these compounds is discussed, on the basis of spectroscopic evidence and study of their chemical reactivity.