1365175-53-6

Basic information

• Product Name: 2-benzothiazolylthio-3-phenylpropanal
• Synonyms: 2-benzothiazolylthio-3-phenylpropanal
• CAS NO: 1365175-53-6
• Molecular Weight: 299.417
• Mol File: 1365175-53-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-benzothiazolylthio-3-phenylpropanal(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzothiazolylthio-3-phenylpropanal(1365175-53-6)
• EPA Substance Registry System: 2-benzothiazolylthio-3-phenylpropanal(1365175-53-6)

Safety Data

• Hazardous Substances Data: 1365175-53-6(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 104-53-0 3-phenyl-propionaldehyde 
• 1365175-36-5 ethyl 2-(2-benzothiazolylsulfinyl)acetate 
• 26773-65-9 N-piperidin-2-benzothiazole sulfenamide 
• 24044-88-0 ethyl 2-(benzo[d]thiazol-2-ylthio)acetate 

Relevant articles and documents

Alkyl 2-(2-benzothiazolylsulfinyl)acetates as useful synthetic reagents for alkyl 4-hydroxyalk-2-enoates by sulfinyl-Knoevenagel reaction

Isopropyl, ethyl, and methyl 2-(2-benzothiazolylsulfinyl)acetates have been found to be useful synthetic reagents for sulfinyl-Knoevenagel reaction with various aldehydes to give directly the corresponding 4-hydroxyalk-2-enoates [R′CH(OH)CHCHCO2R], which are ubiquitous structures in biologically active natural products and useful building blocks for organic synthesis of chiral compounds. From the optically pure (R)-2-(2- benzothiazolylsulfinyl)acetates (>99% ee) prepared by the enzymatic kinetic resolution of (±)-2-(2-benzothiazolylsulfinyl)acetates, optically active 4-hydroxyalk-2-enoates (up to 91% ee) have been obtained in good yields.