136520-80-4

Upstream product

• 124322-00-5 ((1S,2S,4S)-2-(tert-Butyl-dimethyl-silanyloxy)-1-cyclohexylmethyl-5-methyl-4-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexyl)-carbamic acid tert-butyl ester 

Downstream Products

• 124322-01-6 (S)-2-tert-Butoxycarbonylamino-N-((1S,2S,4S)-1-cyclohexylmethyl-2-hydroxy-5-methyl-4-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexyl)-succinamic acid benzyl ester 
• 124322-04-9 (S)-N-((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-5-methyl-4-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexyl)-2-(2-phenoxy-acetylamino)-succinamic acid benzyl ester 
• 124322-03-8 (S)-N-((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-5-methyl-4-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexyl)-2-phenylacetylamino-succinamic acid benzyl ester 
• 124321-73-9 (S)-N-((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-5-methyl-4-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexyl)-2-(2-phenoxy-acetylamino)-succinamic acid 
• 124321-77-3 (S)-N-((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-5-methyl-4-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexyl)-2-phenylacetylamino-succinamic acid 
• 124322-02-7 (S)-2-Amino-N-((1S,2S,4S)-1-cyclohexylmethyl-2-hydroxy-5-methyl-4-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexyl)-succinamic acid benzyl ester 

Relevant academic research and scientific papers

Renin Inhibitory Peptides. A β-Aspartyl Residue as a Replacement for the Histidyl Residue at the P-2 Site

In an effort to decrease the size and to increase the hydrophilicity of the previously prepared renin inhibitory peptides, it was postulated that one might be able to take advantage of the polar Thr-84 on the flap region of the enzyme renin by potential h