1365258-95-2Relevant academic research and scientific papers
PREPARATION OF 2-METHYL-4-AMINO-5(SUBSTITUTED-1H-1,2,3-TRIAZOLYL)METHYLPYRIMIDINE DERIVATIVES AND MICROBICIDAL ACTIVITY THEREOF
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Paragraph 0031-0037; 0064-0070, (2014/07/22)
Disclosed is a derivative of 2-methyl-4-amino-5-(substituted-1H-1,2,3-triazol)methylpyrimidine of general formula I and microbicidal activity thereof. In the formula, R1 represents hydrogen, I; X represents O or NH; Y represents phenyl of substituted phen
Design, synthesis and biological evaluation of novel 2-methylpyrimidine-4- ylamine derivatives as inhibitors of Escherichia coli pyruvate dehydrogenase complex E1
He, Junbo,Feng, Lingling,Li, Jing,Tao, Ruijuan,Wang, Fang,Liao, Xun,Sun, Qiushuang,Long, Qingwu,Ren, Yanliang,Wan, Jian,He, Hongwu
, p. 1665 - 1670 (2012/04/10)
As potential inhibitors of Escherichia coli pyruvate dehydrogenase complex E1 (PDHc E1), a series of novel 2-methylpyrimidine-4-ylamine derivatives were designed based on the structure of the active site of PDHc E1 and synthesized using 'click chemistry'.
