1365354-76-2

Basic information

• Product Name: 3-isopropyl-4-nitro-1H-pyrazole-5-carboxylic acid
• Synonyms: 1H-Pyrazole-5-carboxylic acid, 3-(1-methylethyl)-4-nitro-
• CAS NO: 1365354-76-2
• Molecular Formula: C7H9N3O4
• Molecular Weight: 199.16406
• Mol File: 1365354-76-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-isopropyl-4-nitro-1H-pyrazole-5-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-isopropyl-4-nitro-1H-pyrazole-5-carboxylic acid(1365354-76-2)
• EPA Substance Registry System: 3-isopropyl-4-nitro-1H-pyrazole-5-carboxylic acid(1365354-76-2)

Safety Data

• Hazardous Substances Data: 1365354-76-2(Hazardous Substances Data)

Upstream product

• 563-80-4 3-methyl-butan-2-one 
• 92933-47-6 3-(1-methylethyl)-1H-pyrazole-5-carboxylic acid 

Downstream Products

• 611211-01-9 7-hydroxy-3-isopropylpyrazolo[4,3-d]pyrimidine 
• 607729-10-2 3-isopropyl-1⁽²⁾H-pyrazolo[4,3-d]pyrimidin-5,7-diol 
• 521300-01-6 5-isopropyl-4-nitro-1⁽²⁾H-pyrazole-3-carboxamide 

Relevant articles and documents

INDOLE AHR INHIBITORS AND USES THEREOF

The present invention provides compounds useful as inhibitors of AHR, compositions thereof, and methods of using the same.

Synthesis, antibacterial activity and structure-activity relationship of N-substituted 4-diazo-pyrazole-5-carboxamides. 2

A series of 4-diazopyrazole-5-carboxamides 1 d-n has been synthesized and their antibacterial activity against a number of Gram-negative and Gram-positive strains has been tested. Some of the compounds resulted quite active and the whole set allowed to further study the SAR of the class. Substituents in position 5 affect Gram-negative and Gram-positive activities via bulk and electronic properties respectively; position 3 mostly affects the Gram-negative activity, while the presence of the charged diazo group in position 4 is crucial for both antibacterial activities.