1365354-76-2Relevant articles and documents
INDOLE AHR INHIBITORS AND USES THEREOF
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Paragraph 00290-00291, (2018/11/22)
The present invention provides compounds useful as inhibitors of AHR, compositions thereof, and methods of using the same.
Synthesis, antibacterial activity and structure-activity relationship of N-substituted 4-diazo-pyrazole-5-carboxamides. 2
Baraldi,Cacciari,Leoni,Recanatini,Roberti,Rossi,Manfredini,Periotto,Simoni
, p. 1337 - 1350 (2007/10/02)
A series of 4-diazopyrazole-5-carboxamides 1 d-n has been synthesized and their antibacterial activity against a number of Gram-negative and Gram-positive strains has been tested. Some of the compounds resulted quite active and the whole set allowed to further study the SAR of the class. Substituents in position 5 affect Gram-negative and Gram-positive activities via bulk and electronic properties respectively; position 3 mostly affects the Gram-negative activity, while the presence of the charged diazo group in position 4 is crucial for both antibacterial activities.