136538-94-8 Usage
General Description
4-Thiazolecarboxylic acid, 5-amino-2-chloro-, methyl ester (9CI) is a chemical compound with the molecular formula C6H6ClN3O2S. It is a methyl ester derivative of 5-amino-2-chloro-4-thiazolecarboxylic acid and is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 4-Thiazolecarboxylicacid,5-amino-2-chloro-,methylester(9CI) is of interest in medicinal chemistry due to its potential use in the development of therapeutic drugs and has been studied for its various biological activities, including antimicrobial, antifungal, and antitumor properties. The compound's structure and properties make it a valuable building block for the synthesis of more complex organic molecules, making it a versatile and important chemical in the field of pharmaceutical research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 136538-94-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,5,3 and 8 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 136538-94:
(8*1)+(7*3)+(6*6)+(5*5)+(4*3)+(3*8)+(2*9)+(1*4)=148
148 % 10 = 8
So 136538-94-8 is a valid CAS Registry Number.
136538-94-8Relevant articles and documents
An Unusual Labilization of a 4-(Trifluoromethyl)thiazole
South, Michael S.
, p. 1013 - 1016 (2007/10/02)
N-2-Chloro-4-(trifluoromethyl)-5-thiazolyl-N',N'-diethylurea 5 has been found to undergo a facile labilization of the trifluoromethyl group under mild conditions.The reaction relies on the assistance of the nitrogen substitution at the 4-position of the thiazole ring.Treatment of 5 with triethylamine and either methanol or methanethiol replaced the trifluoromethyl group with a methyl ester or a trimethylorthothio ester respectively at room temperature.Combination of 5 with diethylamine led to an unusual thiazolidine with two exocyclic double bonds, 8.
