1365529-69-6Relevant academic research and scientific papers
Rapid additions of bulky tert-butyldimethylsilyl cyanide to hindered ketones promoted by heterogeneous tin ion-exchanged montmorillonite catalyst
Wang, Jiacheng,Masui, Yoichi,Hattori, Taiki,Onaka, Makoto
, p. 1978 - 1981 (2012)
Tin ion-exchanged montmorillonite (Sn-Mont) was found to be a powerful heterogeneous catalyst for the cyanosilylation of various ketones including congested ones with a bulky cyanide source, tert-butyldimethylsilyl cyanide (TBDMSCN), giving the corresponding cyanohydrin tert-butyldimethylsilyl ethers in good (85%) to excellent (>98%) yields at room temperature. Compared to the previously reported catalysts, Sn-Mont is easy to prepare, environmentally benign, nontoxic, noncorrosive, and recyclable.
