1365545-42-1

Basic information

• Product Name: Dutasteride Chloro IMpurity
• Synonyms: (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-[2,5-Bis(trifluoroMethyl)phenyl]-4-chlorohexadecahydro-4a,6a-diMethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxaMide;1-Chloro Dihydro Dutasteride;Dutasteride Chloro IMpurity;Dutasteride IMpurity D (1-Chloro Dihydro Dutasteride);Dutasteride Impurity D;17β-N-[2,5-Bis(trifluoromethyl)phenyl]-1-chloro-3-oxo-4-azaandrost-17-carboxamide
• CAS NO: 1365545-42-1
• Molecular Formula: C27H31ClF6N2O2
• Molecular Weight: 564.9906592
• Product Categories: Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids
• Mol File: 1365545-42-1.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 645.6±55.0 °C(Predicted)
• Appearance: /
• Density: 1.37±0.1 g/cm3(Predicted)
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Sparingly)
• PKA: 13.33±0.70(Predicted)
• CAS DataBase Reference: Dutasteride Chloro IMpurity(CAS DataBase Reference)
• NIST Chemistry Reference: Dutasteride Chloro IMpurity(1365545-42-1)
• EPA Substance Registry System: Dutasteride Chloro IMpurity(1365545-42-1)

Safety Data

• Hazardous Substances Data: 1365545-42-1(Hazardous Substances Data)

Usage

Description

Dutasteride Chloro IMpurity, also known as 1-Chloro Dihydro Dutasteride, is a 3-oxo-4-aza-5α-androstene-17β-carboxylic acid derivative. It is identified as an impurity of Dutasteride (D735000), a medication primarily used for treating benign prostatic hyperplasia and androgenetic alopecia.

Uses

Used in Pharmaceutical Industry:
Dutasteride Chloro IMpurity is used as a reference compound for the development and quality control of Dutasteride. It helps in ensuring the purity and efficacy of the final drug product by providing a benchmark for comparison during the manufacturing process.
Used in Research and Development:
Dutasteride Chloro IMpurity is used as a research compound in the field of pharmaceuticals and medicinal chemistry. It aids scientists in understanding the structure-activity relationship of Dutasteride and its analogs, potentially leading to the discovery of new drugs with improved properties.
Used in Quality Control and Regulatory Compliance:
Dutasteride Chloro IMpurity is used as a testing material in the quality control of Dutasteride products. It helps in assessing the effectiveness of purification processes and ensuring that the drug meets the required regulatory standards for safety and efficacy.