1365655-66-8

Upstream product

• 1365655-81-7 (3R,3aR,5R,6aR)-3-acetamidohexahydro-2H-cyclopenta[b]furan-5-yl 4-nitrophenyl carbonate 
• 159005-71-7 N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-methoxybenzenesulfonamide 
• 1365655-74-8 N-((3S,3aR,5R,6aR)-5-hydroxyhexahydro-2H-cyclopenta[b]furan-3-yl)-acetamide 

Relevant academic research and scientific papers

C-3 SUBSTITUTED BICYCLOOCTANE BASED HIV PROTEASE INHIBITORS

C3-functionalized-cyclopentanyltetrahydrofuranyl carbamates that inhibit HIV proteolytic enzymes and processes for preparing the compounds are described. Compositions comprising the disclosed compound and methods of using the compounds and/or compositions for treating patients infected with HIV are also described.

Substituent effects on P2-cyclopentyltetrahydrofuranyl urethanes: Design, synthesis, and X-ray studies of potent HIV-1 protease inhibitors

The design, synthesis, and biological evaluation of novel C3-substituted cyclopentyltetrahydrofuranyl (Cp-THF)-derived HIV-1 protease inhibitors are described. Various C3-functional groups on the Cp-THF ligand were investigated in order to maximize the li