Biotin-PEG2-Acid, also known as Biotinylated PEG2 Acid, is a chemical compound that features a biotin molecule linked to a polyethylene glycol (PEG) chain with a terminal carboxylic acid group. This molecule is designed to be reactive with amine-containing macromolecules, such as proteins or other biomolecules. The hydrophilic PEG arm enhances the water solubility of the compound, while the biotin groups provide a strong affinity label towards proteins like avidin and streptavidin, making it a versatile tool in various applications.
1365655-89-5
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Basic information
- Product Name: Biotin-PEG2-Acid
- Synonyms: Biotin-PEG2-Acid;(+)-Biotin-PEG2-CH2CH2COOH;Biotin-PEG2-COOH
- CAS NO:1365655-89-5
- Molecular Formula: C17H29N3O6S
- Molecular Weight: 403.49366
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1365655-89-5.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 752.2±60.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.234±0.06 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: Soluble in DMSO, DMF
- PKA: 4.28±0.10(Predicted)
- CAS DataBase Reference: Biotin-PEG2-Acid(CAS DataBase Reference)
- NIST Chemistry Reference: Biotin-PEG2-Acid(1365655-89-5)
- EPA Substance Registry System: Biotin-PEG2-Acid(1365655-89-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1365655-89-5(Hazardous Substances Data)
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1365655-89-5 Usage
Uses
Used in Biomedical Research:Biotin-PEG2-Acid is used as a labeling agent for the detection and purification of amine-containing macromolecules. The biotin group allows for easy detection through the strong interaction with avidin or streptavidin, which can be conjugated to detection systems like fluorescent dyes or enzymes for signal amplification.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Biotin-PEG2-Acid is used as a component in the design of targeted drug delivery systems. The biotin-avidin interaction can be exploited to enhance the specificity of drug delivery, ensuring that therapeutic agents are preferentially taken up by cells expressing high levels of avidin or related proteins.
Used in Diagnostics:
Biotin-PEG2-Acid is employed as a component in the development of diagnostic assays, particularly those involving the detection of specific proteins or other biomolecules. The strong biotin-avidin interaction can be used to amplify signals, improving the sensitivity and accuracy of diagnostic tests.
Used in Chemical Synthesis:
In the field of chemical synthesis, Biotin-PEG2-Acid can be used as a building block to create biotinylated conjugates with various applications, such as in the development of new drugs, imaging agents, or research tools.
Used in Cosmetics and Personal Care:
Biotin-PEG2-Acid can be utilized in the cosmetics and personal care industry as an ingredient in skin care products, where it may enhance the delivery of active ingredients to the skin and improve the overall efficacy of the product.
Check Digit Verification of cas no
The CAS Registry Mumber 1365655-89-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,6,5,6,5 and 5 respectively; the second part has 2 digits, 8 and 9 respectively.Calculate Digit Verification of CAS Registry Number 1365655-89:
(9*1)+(8*3)+(7*6)+(6*5)+(5*6)+(4*5)+(3*5)+(2*8)+(1*9)=195
195 % 10 = 5
So 1365655-89-5 is a valid CAS Registry Number.
1365655-89-5Upstream product
1365655-89-5Downstream Products
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Biotin-PEG2-Acid
