13659-00-2Relevant academic research and scientific papers
Microwave-assisted cyclizations promoted by polyphosphoric acid esters: A general method for 1-aryl-2-iminoazacycloalkanes
Díaz, Jimena E.,Mollo, María C.,Orelli, Liliana R.
supporting information, p. 2026 - 2031 (2016/10/05)
The first general procedure for the synthesis of 5 to 7-membered 1-aryl-2-iminoazacycloalkanes is presented, by microwave-assisted ring closure of ω-arylaminonitriles promoted by polyphosphoric acid (PPA) esters. 1-Aryl-2-iminopyrrolidines were easily pre
1,n-Diamines. Part 4: Synthesis of 1-aryl-2-alkyl-1,4,5,6,7,8-hexahydro-1, 3-diazocines
Díaz, Jimena E.,Gruber, Nadia,Orelli, Liliana R.
supporting information; experimental part, p. 6443 - 6445 (2012/01/19)
In this Letter we present the synthesis of hitherto unreported 1-aryl-2-alkyl-1,4,5,6,7,8-hexahydro-1,3-diazocines 1. Cyclic amidines 1 were synthesized by PPSE promoted ring closure of N-acyl-N'-arylpen- tamethylenediamines 2. The cyclodehydration reacti
An efficient synthesis of N-arylputrescines and cadaverines
Link, Natalia P.,Díaz, Jimena E.,Orelli, Liliana R.
experimental part, p. 751 - 754 (2009/07/18)
We present a two-step, general synthesis of N-aryl-putrescines and cadaverines, by cesium carbonate mediated alkylation of anilines with ω-chloronitriles and subsequent reduction. The cesium-mediated alkylation shows remarkable selectivity towards the mon
