1365910-91-3

Basic information

• Product Name: 4-methyl-N-(p-tolyl)naphthalen-1-amine
• Synonyms: 4-methyl-N-(p-tolyl)naphthalen-1-amine
• CAS NO: 1365910-91-3
• Molecular Weight: 247.34
• Mol File: 1365910-91-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-methyl-N-(p-tolyl)naphthalen-1-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-N-(p-tolyl)naphthalen-1-amine(1365910-91-3)
• EPA Substance Registry System: 4-methyl-N-(p-tolyl)naphthalen-1-amine(1365910-91-3)

Safety Data

• Hazardous Substances Data: 1365910-91-3(Hazardous Substances Data)

Upstream product

• 106-49-0 p-toluidine 
• 86-52-2 1-Chloromethylnaphthalene 
• 66-77-3 1-naphthaldehyde 
• 16413-71-1 N,N-dimethyl(naphthalen-1-yl)methanamine 

Relevant articles and documents

Palladium-Catalyzed Highly Regioselective Aromatic Substitution of Benzylic Ammonium Salts with Amines

An unprecedented aromatic substitution reaction of benzylic ammonium salts has been developed through palladium-catalyzed C-N bond cleavage. A range of primary and secondary amines participated in a palladium-catalyzed aromatic substitution reaction of benzylic ammonium salts, delivering sterically hindered aromatic amines in moderate to excellent yields with extremely high regioselectivity. Preliminary mechanistic studies permitted successful identification of Π-benzylpalladium complexes and Γ-vinyl allylic amines as key intermediates. This study paves the way for the use of benzylic ammonium salts in the aromatic substitution reactions.