1365997-65-4

Upstream product

• 1365998-58-8 3-(2,5-difluoro-4-(methylsulfonyl)phenoxy)-1-(1-(3-isopropyl-1,2,4-oxadiazol-5-yl)piperidin-4-yl)pyrrolidin-2-one 
• 1365998-57-7 4-(3-(2,5-difluoro-4-(methylsulfonyl)phenoxy)-2-oxopyrrolidin-1-yl)piperidine-1-carbonitrile 
• 1365998-55-5 tert-butyl 4-(3-(2,5-difluoro-4-(methylsulfonyl)phenoxy)-2-oxopyrrolidin-1-yl)piperidin-1-carboxylate 
• 1365998-54-4 tert-butyl 4-(3-(4-bromo-2,5-difluorophenoxy)-2-oxopyrrolidin-1-yl)piperidin-1-carboxylate 
• 1365998-53-3 tert-butyl 4-(2,4-dibromobutanamido)piperidin-1-carboxylate 
• 1365998-56-6 3-(2,5-difluoro-4-(methylsulfonyl)phenoxy)-1-(piperidin-4-yl)pyrrolidin-2-one 
• 1351168-97-2 tert-butyl 4-(3-bromo-2-oxo-pyrrolidin-1-yl)piperidine-1-carboxylate 
• 87120-72-7 1-(tert-butoxycarbonyl)-4-aminopiperidine 

Relevant academic research and scientific papers

PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS

Compounds of Formula (I) and pharmaceutically acceptable salts thereof in which X1, X2, L, R3, R4, R5, R7 and n have the meanings given in the specification, are modulators of GPR119 and are useful in the treatment or prevention of diseases such as such as, but not limited to, type 2 diabetes, diabetic complications, symptoms of diabetes, metabolic syndrome, obesity, dyslipidemia, and related conditions.