1366005-16-4

Upstream product

• 37942-07-7 3,5-di-tert-butyl-2-hydroxybenzaldehyde 
• 53273-24-8 (1S,2S,5R)-(+)-neomenthyl thiol 

Downstream Products

• 1366005-32-4 (S,1S,2S,5R)-N-(3,5-di-tert-butyl-2-hydroxybenzyl)-2-isopropyl-5-methylcyclohexanesulfinamide 

Relevant academic research and scientific papers

New N-substituted sulfinamides of neomenthane series

A reaction of neomenthanethiol with ammonia and N-chlorosuccinimide with subsequent addition of aromatic aldehydes leads to chiral N- arylideneneomenthylsulfenimines, whose oxidation at the sulfur atom gives N-arylideneneomenthylsulfinimines. The reactions of N- arylideneneomenthylsulfinimines with lithium aluminum hydride or Grignard reagents proceed at the imine fragment and lead to the corresponding N-benzylneomenthylsulfinamides.

Asymmetric synthesis of new optically active sulfinamides of menthane series and their derivatives

Asymmetric syntheses were performed of neomenthanesulfi namide in the yield of 60% and de 74%, of neomenthanesulfi naldimines and N-substituted neomenthanesulfi namides in 22-80 and 40-90% yields respectively. Pleiades Publishing, Ltd., 2012.