136605-73-7Relevant academic research and scientific papers
Systematic study of effects of structural modifications on the aqueous solubility of drug-like molecules
Cisneros, Jose A.,Robertson, Michael J.,Mercado, Brandon Q.,Jorgensen, William L.
, p. 124 - 127 (2017)
Aqueous solubilities and activities have been measured for 17 members of the quinolinyltriazole series of inhibitors of human macrophage migration inhibitory factor (MIF). Systematic variation of a solvent-exposed substituent provided increases in solubil
POM@IL-MOFs-inclusion of POMs in ionic liquid modified MOFs to produce recyclable oxidation catalysts
Abednatanzi, Sara,Leus, Karen,Derakhshandeh, Parviz Gohari,Nahra, Fady,De Keukeleere, Katrien,Van Hecke, Kristof,Van Driessche, Isabel,Abbasi, Alireza,Nolan, Steven P.,Der Voort, Pascal Van
, p. 1478 - 1487 (2017)
In this study, we present for the first time the immobilization of phosphotungstic acid (H3PW12O40, HPW) into the nanocages of a dual amino-functionalized ionic liquid (DAIL)-modified MIL-101(Cr) framework under mild condi
SOLVENT-LESS IONIC LIQUID EPOXY RESIN
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Page/Page column 13, (2018/05/17)
Solvent free epoxy system that includes: a hardener compound H comprising: a molecular structure (Y1-R1-Y2), wherein R1 is an ionic moiety Y1 is a nucleophilic group and Y2 nucleophilic gro
HETEROCYCLIC COMPOUND
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Paragraph 0594, (2015/01/18)
The present invention provides an agent for the prophylaxis or treatment of autoimmune diseases (e.g., psoriasis, rheumatoid arthritis, inflammatory bowel disease, Sjogren's syndrome, Behcet's disease, multiple sclerosis, systemic lupus erythematosus etc.) and the like, which has a superior Tyk2 inhibitory action. The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.
2-AMINOPYRIMIDINE-4-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN URINARY THERAPEUTICS
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, (2008/06/13)
A compound of formula (I) STR1 in which n denotes 2, 3, 4, or 5, p denotes 0 or 1,m denotes 0, 1, 2, 3, 4, or 5, and R 1 denotes a hydrogen atom or a methyl group,each X, which may be identical or different to any other X if m is greater than 1, denotes fluorine, chlorine, methoxy, isopropyl or cyclopropyl,in the form of a free base or an acid addition salt.
