136611-38-6Relevant articles and documents
Microwave-Assisted Catalyst Free Three Component Synthesis of Mono and Bis Spiro Pyrazolopyridines in Solvent Free Reaction
Nikpassand, Mohammad,Zare Fekri, Leila,Jamshidi, Neda
, p. 1580 - 1583 (2015)
Multicomponent synthesis of mono and bis-spiro pyrazolopyridines from isatin derivatives, indanedione, and 3-methyl-5-aminopyrazole under microwave irradiation in the absence of any catalyst or solvent with high yield and short reaction time is reported.
Hantzsch reaction with bis-indole-2,3-diones: Synthesis of novel bis-spirocyclic oxindole incorporating acridine, dipyrazolo[3,4-b:4',3'-e]pyridine and pyrido[2,3-d:6,5-d']dipyrimidine
Abdelmoniem, Amr M.,Abdelrahman, Mohamed G. M.,Ghozlan, Said A. S.,Elwahy, Ahmed H. M.,Abdelhamid, Ismail A.
, p. 1814 - 1824 (2021)
One-pot three-component cyclo-condensation reaction of bis(indole-2,3-diones) with dimedone, 3-methyl-1H-pyrazol-5(4H)-one, or 6-aminouracil in boiling acetic acid afforded bis-spirocyclic oxindoles linked to acridine, dipyrazolo[3,4-b:4',3'-e]pyridine, a
DIMERS OF COVALENT NFKB INHIBITORS
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Paragraph 00107; 00108, (2018/07/29)
Provided herein are compounds and methods for modulating the NF?B pathway. More particularly, provided are inhibitors of the NF?B pathway and the uses of such inhibitors in regulating diseases and disorders, e.g., to treat cancer, autoimmune diseases, inflammatory diseases, diabetes, cardiovascular diseases, or neurological diseases.
Highly efficient, one-pot synthesis of novel bis-spirooxindoles with skeletal diversity: Via sequential multi-component reaction in PEG-400 as a biodegradable solvent
Safari, Ensieh,Maryamabadi, Ammar,Hasaninejad, Alireza
, p. 39502 - 39511 (2017/08/26)
A green and efficient one-pot, sequential, multi-component protocol has been developed for the synthesis of some novel symmetrical bis-spirooxindole derivatives from the reaction of isatins, dihalides, malono derivatives and C-H activated carbonyl compoun
