136616-99-4Relevant academic research and scientific papers
Regioselectivity in the Reaction of Tantalum-Unsymmetrical Acetylene Complexes with Carbonyl Compounds. Stereoselective Preparation of 1-Alkenyl Sulfides, α,β-Unsaturated Esters, and Amides
Kataoka, Yasutaka,Miyai, Jiro,Tezuka, Makoto,Takai, Kazuhiko,Utimoto, Kiitiro
, p. 6796 - 6802 (2007/10/02)
Tantalum-alkyne complexes, derived by treatment of alkynes with low-valent tantalum (TaCl5 and zinc), react in situ with carbonyl compounds to give (E)-allylic alcohols stereoselectively.When unsymmetrical acetylenes are employed in the reaction, two regi
Stereoselective Synthesis of Trisubstituted α,β-Unsaturated Esters and Amides via Reactions of Tantalum-Alkyne Complexes Derived from Acetylenic Esters and Amides with Carbonyl Compounds
Takai, Kazuhiko,Tezuka, Makoto,Utimto, Kiitiro
, p. 5980 - 5982 (2007/10/02)
Treatment of acetylenic esters with low-valent tantalum (TaCl5 and Zn) in DME and benzene produces tantalum-alkyne complexes (not isolated), which react with carbonyl compounds regioselectively at the α-position of the esters to give Z isomers of trisubstituted α,β-unsaturated esters in a stereoselective manner.In contrast, tantalum-alkyne complexes derived from acetylenic amides react with carbonyl compounds at the β-position of the amides predominantly.
