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4-hydroxy-2-[2'-(morpholin-4-ylmethyl)biphenyl-4-yl]-1,6-naphthyridine-3-carbonitrile is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1366180-75-7

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1366180-75-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1366180-75-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,6,6,1,8 and 0 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1366180-75:
(9*1)+(8*3)+(7*6)+(6*6)+(5*1)+(4*8)+(3*0)+(2*7)+(1*5)=167
167 % 10 = 7
So 1366180-75-7 is a valid CAS Registry Number.

1366180-75-7Downstream Products

1366180-75-7Relevant academic research and scientific papers

Discovery of 4-hydroxy-1,6-naphthyridine-3-carbonitrile derivatives as novel PDE10A inhibitors

Bauer, Udo,Giordanetto, Fabrizio,Bauer, Martin,O'Mahony, Gavin,Johansson, Kjell E.,Knecht, Wolfgang,Hartleib-Geschwindner, Judith,Carlsson, Eva T?ppner,Enroth, Cristofer

supporting information; experimental part, p. 1944 - 1948 (2012/04/17)

A series of 1,6-naphthyridine-based compounds was synthesized as potent phosphodiesterase 10A (PDE10A) inhibitors. Structure-based chemical modifications of the discovered chemotype served to further improve potency and selectivity over DHODH, laying the foundation for future optimization efforts.

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