1366360-76-0Relevant academic research and scientific papers
Synthesis of a benzannulated pyrrolizidine by a copper-catalyzed intramolecular α-Arylation reaction
Magalhaes Araujo, Flavia,Martins Ventura, Wellington,Guy Taylor, Jason
, p. 569 - 573 (2014)
A synthetic route to the pyrrolo[1,2-a]indole ring system (benzannulated pyrrolizidine) involving a base-induced intramolecular aza-Michael reaction as the key C-N bond-forming penultimate step, followed by a Cu-catalyzed intramolecular α-arylation reacti
Expedient access to an N-phenylpyrrolidin-2-yl heterocycle via a base-induced intramolecular aza-michael reaction
Ferreira Ramos, Josierika A.,Nagem, Tanus J.,Taylor, Jason G.
, p. 225 - 230 (2012/03/11)
Ethyl 2-(1-phenylpiperidin-2-yl) acetate was formed in a spontaneous cyclization from (E)-ethyl 7-oxohept-2-enoate whereas ethyl [1-(2-bromophenyl)- 2-pyrrolidinyl] acetate could be synthesized in good overall yield when employing a stoichiometric amount of base to facilitate the intramolecular aza-Michael reaction.
