136638-77-2Relevant academic research and scientific papers
PHASE-TRANSFER CATALYZED ALKOXYLATION OF 2-(DICHLOROMETHYL)FURAN BY ALCOHOLS IN THE PRESENCE OF POTASSIUM HYDROXIDE
Shavrin, K. N.,Volotova, I. V.,Kutin, A. A.
, p. 1244 - 1248 (1991)
Reaction of 2-(dichloromethyl)furan (I) with KOH in a CH2Cl2 medium and in the presence of alcohols (methanol, ethanol, and n-butanol) and a catalytic amount of triethylbenzylammonium chloride (TEBAC) results in the formation of 2-chloromethylene-5-alkoxy-2,5-dihydrofurans (II) (mixtures of Z- and E-isomers) and 2-dialkoxymethylfurans (III), in overall yields of up to 96percent.Reaction with isopropyl and tert-butyl alcohols gave only corresponding products (II), in 21 and 12percent yield, respectively.
