Alpha-defensin-3 (human) is a small antimicrobial peptide that is part of the defensin family, playing a crucial role in innate immune defense. It is produced by neutrophils and is present in various tissues and bodily fluids, such as the skin, respiratory tract, and digestive system. This peptide is effective against a broad spectrum of pathogens, including bacteria, fungi, and viruses, by disrupting their cell membranes. Additionally, it possesses immunomodulatory and anti-inflammatory properties, which aid in the regulation of the immune response. The therapeutic potential of alpha-defensin-3 is currently being explored for the treatment of infections and inflammatory conditions.
136661-76-2
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Basic information
- Product Name: ALPHA-DEFENSIN-3 (HUMAN)
- Synonyms: Defensin, alpha 3;Neutrophil defensin 3;Defensin HNP-3;ASP-CYS-TYR-CYS-ARG-ILE-PRO-ALA-CYS-ILE-ALA-GLY-GLU-ARG-ARG-TYR-GLY-THR-CYS-ILE-TYR-GLN-GLY-ARG-LEU-TRP-ALA-PHE-CYS-CYS;HNP-3;HUMAN NEUTROPHIL PEPTIDE-3;ALPHA-DEFENSIN-3 (HUMAN);DEFENSIN HNP-3 (HUMAN)
- CAS NO:136661-76-2
- Molecular Formula: C151H222N44O40S6
- Molecular Weight: 3486.04
- EINECS: N/A
- Product Categories: N/A
- Mol File: 136661-76-2.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: 1.54±0.1 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: -20°C
- Solubility: N/A
- CAS DataBase Reference: ALPHA-DEFENSIN-3 (HUMAN)(CAS DataBase Reference)
- NIST Chemistry Reference: ALPHA-DEFENSIN-3 (HUMAN)(136661-76-2)
- EPA Substance Registry System: ALPHA-DEFENSIN-3 (HUMAN)(136661-76-2)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 136661-76-2(Hazardous Substances Data)
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136661-76-2 Usage
Uses
Used in Pharmaceutical Industry:Alpha-defensin-3 (human) is used as an antimicrobial agent for its ability to combat a wide range of pathogens, including bacteria, fungi, and viruses. Its mechanism of action involves disrupting the cell membranes of these pathogens, thereby inhibiting their growth and spread.
Used in Immunotherapy:
In the field of immunotherapy, alpha-defensin-3 (human) is utilized for its immunomodulatory and anti-inflammatory properties. It helps regulate the immune response, making it a potential candidate for the treatment of various inflammatory conditions.
Used in Research:
Alpha-defensin-3 (human) is also used in research settings to study its potential therapeutic applications in the treatment of infections and inflammatory conditions. This includes understanding its mechanism of action, as well as identifying ways to enhance its efficacy and safety for clinical use.
Used in Drug Development:
In the drug development industry, alpha-defensin-3 (human) is being investigated for its potential as a novel therapeutic agent. Researchers are exploring methods to optimize its production, delivery, and stability, as well as assessing its safety and efficacy in preclinical and clinical trials.
Overall, alpha-defensin-3 (human) is a promising peptide with diverse applications in the pharmaceutical, immunotherapy, research, and drug development industries. Its antimicrobial, immunomodulatory, and anti-inflammatory properties make it a valuable asset in the fight against infections and inflammatory conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 136661-76-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,6,6 and 1 respectively; the second part has 2 digits, 7 and 6 respectively.Calculate Digit Verification of CAS Registry Number 136661-76:
(8*1)+(7*3)+(6*6)+(5*6)+(4*6)+(3*1)+(2*7)+(1*6)=142
142 % 10 = 2
So 136661-76-2 is a valid CAS Registry Number.
136661-76-2Upstream product
136661-76-2Downstream Products
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ALPHA-DEFENSIN-3 (HUMAN)
