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1366642-07-0

4′-bromomarchantin C is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1366642-07-0 Structure

  • Basic information

    1. Product Name: 4′-bromomarchantin C
    2. Synonyms:
    3. CAS NO:1366642-07-0
    4. Molecular Formula:
    5. Molecular Weight: 503.392
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1366642-07-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4′-bromomarchantin C(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4′-bromomarchantin C(1366642-07-0)
    11. EPA Substance Registry System: 4′-bromomarchantin C(1366642-07-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1366642-07-0(Hazardous Substances Data)

1366642-07-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1366642-07-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,6,6,6,4 and 2 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1366642-07:
(9*1)+(8*3)+(7*6)+(6*6)+(5*6)+(4*4)+(3*2)+(2*0)+(1*7)=170
170 % 10 = 0
So 1366642-07-0 is a valid CAS Registry Number.

1366642-07-0Upstream product

1366642-07-0Downstream Products

1366642-07-0Relevant articles and documents

Design, synthesis and biological evaluation of novel macrocyclic bisbibenzyl analogues as tubulin polymerization inhibitors

Sun, Bin,Li, Lin,Hu, Qing-Wen,Xie, Fei,Zheng, Hong-Bo,Niu, Huan-Min,Yuan, Hui-Qing,Lou, Hong-Xiang

, p. 484 - 499 (2016)

A series of novel macrocyclic bisbibenzyl analogues was designed, synthesized, and evaluated for their antiproliferative activity in vitro. All of the compounds were tested in five anthropic cancer cell lines, including a multidrug-resistant phenotype. Among these novel molecules, compounds 88, 92 and 94 displayed excellent anticancer activity against Hela, k562, HCC1428, HT29, and PC-3/Doc cell lines, with average IC50 values ranging from 2.23 μM to 3.86 μM, and were more potent than the parental compound marchantin C and much more potent than the positive control Adriamycin. In addition, the mechanism of action of compound 88 was investigated by cell cycle analysis and a tubulin polymerization assay in HCC1482 cells. The binding mode of compound 88 to tubulin was also investigated utilizing a molecular docking study. In conclusion, the present study improves our understanding of the action of bisbibenzylbased tubulin polymerization inhibitors and provides a new molecular scaffold for the further development of antitumor agents that target tubulin.

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