136675-88-2 Usage
Properties
1. Derived from natural nucleoside zebularine
2. Potential anti-cancer agent
3. Enhanced bioavailability and stability
4. Inhibits growth of cancer cells
5. Interferes with DNA methylation
6. Antiviral and anti-inflammatory properties
Specific content
1. Derived from natural nucleoside zebularine: 2'-arafluorozebularine is a modified chemical compound derived from the natural nucleoside zebularine.
2. Potential anti-cancer agent: It has been developed as a potential anti-cancer agent and has shown promising results in preclinical studies.
3. Enhanced bioavailability and stability: The chemical structure of 2'-arafluorozebularine has been modified to enhance its bioavailability and stability, making it a potential candidate for use in cancer therapies.
4. Inhibits growth of cancer cells: It has been shown to inhibit the growth of cancer cells by interfering with DNA methylation, a key mechanism in cancer development and progression.
5. Antiviral and anti-inflammatory properties: 2'-arafluorozebularine has also been found to have antiviral and anti-inflammatory properties, further expanding its potential medical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 136675-88-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,6,7 and 5 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 136675-88:
(8*1)+(7*3)+(6*6)+(5*6)+(4*7)+(3*5)+(2*8)+(1*8)=162
162 % 10 = 2
So 136675-88-2 is a valid CAS Registry Number.
136675-88-2Relevant articles and documents
Antitumor Properties of 2(1H)-Pyrimidinone Riboside (Zebularine) and Its Fluorinated Analogues
Driscoll, John S.,Marquez, Victor E.,Plowman, Jacqueline,Liu, Paul S.,Kelley, James A.,Barchi, Joseph J.
, p. 3280 - 3284 (2007/10/02)
2(1H)-Pyrimidinone riboside (zebularine, 1b) and its 5-fluoro (6b) and 2'-ara-fluoro (7b) analogues have been synthesized and evaluated in vivo as antitumor agents.Zebularine provides increase in life span (ILS) values of ca. 70percent against intraperito
