136678-89-2

Upstream product

• 13493-50-0 4-hydroxybenzaldehyde benzenesulfonate ester 
• 105959-34-0 (4-Benzenesulfonylamino-benzoylamino)-acetic acid 

Downstream Products

• 136678-87-0 Benzenesulfonic acid 4-[2-(4-benzenesulfonylamino-phenyl)-5-oxo-1-[4-(pyrimidin-2-ylsulfamoyl)-phenyl]-1,5-dihydro-imidazol-(4Z)-ylidenemethyl]-phenyl ester 
• 136678-84-7 Benzenesulfonic acid 4-[2-(4-benzenesulfonylamino-phenyl)-5-oxo-1-(4-sulfamoyl-phenyl)-1,5-dihydro-imidazol-(4Z)-ylidenemethyl]-phenyl ester 
• 136678-85-8 C₃₅H₂₈N₆O₈S₃ 
• 136678-88-1 Benzenesulfonic acid 4-[2-(4-benzenesulfonylamino-phenyl)-1-[4-(4,6-dimethyl-pyrimidin-2-ylsulfamoyl)-phenyl]-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidenemethyl]-phenyl ester 
• 136678-86-9 Benzenesulfonic acid 4-[2-(4-benzenesulfonylamino-phenyl)-5-oxo-1-[4-(pyridin-2-ylsulfamoyl)-phenyl]-1,5-dihydro-imidazol-(4Z)-ylidenemethyl]-phenyl ester 

Relevant academic research and scientific papers

SULFONATE ESTER-CONTAINING (IMIDAZOL-1-yl)-N-SUBSTITUTED BENZENESULFONAMIDES OF ANTICIPATED ANTINEOPLASTIC ACTIVITY

The stereospecific synthesis for a series of (Z)-4--4,5-dihydro-5-oxo-1H-imidazol-1-yl>-N-substituted benzenesulfonamide derivatives (VIa-o) was investigated with a view to prepare new pharmacologically active products of extended and/or improved antineoplastic activity.Owing to the weak nucleophilicity of the nitrogen nucleophiles under investigation, acetic acid mediatd cyclizations were followed for preparation of the required products.Additionally, the antimicrobial activity was screened for the compounds reported.Key words: Sulfonamide derivatives; stereospecific synthesis; antimicrobial activity