1367074-77-8Relevant articles and documents
Intramolecular hydrogen bonding: A potential strategy for more bioavailable inhibitors of neuronal nitric oxide synthase
Labby, Kristin Jansen,Xue, Fengtian,Kraus, James M.,Ji, Haitao,Mataka, Jan,Li, Huiying,Martásek, Pavel,Roman, Linda J.,Poulos, Thomas L.,Silverman, Richard B.
experimental part, p. 2435 - 2443 (2012/05/20)
Selective neuronal nitric oxide synthase (nNOS) inhibitors have therapeutic applications in the treatment of numerous neurodegenerative diseases. Here we report the synthesis and evaluation of a series of inhibitors designed to have increased cell membran