1367182-07-7

Upstream product

• 635-22-3 4-Chloro-3-nitroaniline 
• 90-02-8 salicylaldehyde 

Downstream Products

• 1367182-17-9 2-[(2-hydroxy-phenylimino)-methyl]-4-(4-chloro-3-nitro-phenylazo)-phenol 
• 1399303-04-8 1-{3-[(3-hydroxypropylimino)methyl]-4-hydroxyphenylazo}-4-chloro-3-nitrobenzene 
• 1426125-25-8 1-{3-[(2-hydroxyethoxyethylimino)methyl]-4-hydroxyphenylazo}-4-chloro-3-nitrobenzene 

Relevant academic research and scientific papers

Synthesis and studies of selective chemosensors for anions and cations by azo-containing salicylaldimine-based receptors

Three new chromogenic receptors containing electron-withdrawing groups appended to the azophenol moiety were synthesized, characterized, and their chromogenic behavior toward various anions and cations investigated. These chemosensors show visual changes towards biologically relevant anions like F- and OH-, and also towards various cations such as Cu2+, Co2+, Ni2+, Mn2+, and Zn2 +. Yet, other anions such as Cl-, Br-, and NO3- could not cause any color change. The sensing action was further confirmed by UV-Vis titration. 1H-NMR experiments were carried out to explore the nature of interaction between receptors with F- and OH -. The binding constants (Ka) of the host-guest complexes formed were determined.

Synthesis, spectroscopy, thermal analysis, magnetic properties and biological activity studies of Cu(II) and Co(II) complexes with Schiff base dye ligands

Three azo group-containing Schiff base ligands, namely 1-{3-[(3- hydroxypropylimino) methyl]-4-hydroxyphenylazo}-4-nitrobenzene (2a), 1-{3-[(3-hydroxypropylimino) methyl]-4-hydroxyphenylazo}-2-chloro-4-nitrobenzene (2b) and 1-{3-[(3-hydroxypropylimino) methyl]-4-hydroxyphenylazo}-4-chloro-3- nitrobenzene (2c) were prepared. The ligands were characterized by elemental analysis, FTIR spectroscopy, UV-Vis spectroscopy, 13C- and 1H-NMR spectroscopy and thermogravimetric analysis. Next the corresponding copper(II) and cobalt(II) metal complexes were synthesized and characterized by the physicochemical and spectroscopic methods of elemental analysis, FTIR spectroscopy, UV-Vis spectroscopy, magnetic moment measurements, and thermogravimetric analysis (TGA) and (DSC). The room temperature effective magnetic moments of complexes are 1.45, 1.56, 1.62, 2.16, 2.26 and 2.80 B.M. for complexes 3a, 3b, 3c, 4a 4b, and 4c, respectively, indicating that the complexes are paramagnetic with considerable electronic communication between the two metal centers.

Synthesis and biological activity evaluation of some binuclear metal complexes of Cu(II) and Zn(II) with tridentate schiff base ligands

A few kinds of new Schiff bases were synthesized by reaction of 2-aminophenol and corresponding synthesized azo compounds 3a-e. Further reaction of these Schiff bases 4a-e with transition metal salts as Cu(II) and Zn(II) gave corresponding binuclear complexes 5a-e and 6a-e. The antibacterial activity of prepared complexes was investigated against Staphylococcus aureus and Escherichia coli bacteria. The results for some compounds revealed a moderate to good inhibition against Staphylococcus aureus compared with penicillin zone of inhibition.