1367369-22-9Relevant articles and documents
A highly chemo- and enantioselective nitroaldol reaction of haloenals: Preparation of chiral functionalized allylic alcohols
Gu, Lianghu,Zhou, Yirong,Zhang, Jingli,Gong, Yuefa
experimental part, p. 124 - 129 (2012/05/20)
An efficient L1/Cu(II)-catalyzed highly chemoselective and enantioselective nitroaldol reaction of α- or β-haloenals with nitromethane has been described. The reaction delivered chiral functionalized allylic alcohols bearing halo and nitro groups with excellent results (up to 94% yield and 99% ee) under mild reaction conditions.