136749-56-9 Usage
Molecular Weight
315.38 g/mol
Structure
Spiro compound with a dioxane ring and an azaspiro decane ring
Dioxane ring
A six-membered ring with two oxygen atoms
Azaspiro decane ring
A seven-membered ring containing one nitrogen atom
Methyl group
A single carbon atom (-CH3) attached to the molecule
Hydroxyphenyl group
A phenyl group (C6H5) with two hydroxyl groups (-OH) attached to the 3 and 4 positions
Chirality
The compound is chiral, with the (S) enantiomer being the active form
Stereochemistry
The (S)-configuration indicates the spatial arrangement of the atoms in the molecule
Potential Applications
Pharmaceutical applications due to its unique structure and properties
Optical Activity
The (S) enantiomer may exhibit optical activity, meaning it can rotate plane-polarized light
Solubility
The solubility of 1,4-Dioxa-8-azaspiro[4.5]decan-2-one,
3-[(3,4-dihydroxyphenyl)methyl]-8-methyl-, (S)- may vary depending on the solvent used, but it is likely to be more soluble in organic solvents like ethanol or methanol
Stability
The stability of the compound may depend on factors such as temperature, pH, and exposure to light or air. It is important to store and handle the compound according to recommended guidelines to maintain its integrity.
Check Digit Verification of cas no
The CAS Registry Mumber 136749-56-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,7,4 and 9 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 136749-56:
(8*1)+(7*3)+(6*6)+(5*7)+(4*4)+(3*9)+(2*5)+(1*6)=159
159 % 10 = 9
So 136749-56-9 is a valid CAS Registry Number.
136749-56-9Relevant academic research and scientific papers
Chiral 2-Benzopyran-3-carboxylates by Oxa-Pictet-Spengler Reaction of (S)-3-Phenyllactic Acid Derivatives
Wuensch, Bernhard,Zott, Matthias
, p. 39 - 46 (2007/10/02)
Starting with (S)-tyrosine, the methyl (S)-3-(3,4-dihydroxyphenyl)lactate (15b) was prepared by acylation, desamination and Dakin oxidation.The phenyl moiety of 15b was sufficiently activated for the reaction with aromatic and aliphatic aldehydes and ketones to yield the alkyl (3S)-2-benzopyran-3-carboxylates 16 and 19.On the other hand, the oxa-Pictet-Spengler reaction of the aryl unsubstituted (S)-3-phenyllactic acid (6) succeeds only with aromatic aldehydes.It was shown that the enantiomeric purity of the compounds 13, 14, 15, 16 and 19 was greater than 96percent ee. Key Words: Oxa-Pictet-Spengler reaction / (S)-3-Phenyllactates / (3S)-2-Benzopyran-3-carboxylates
