1367579-50-7Relevant academic research and scientific papers
The Rhodadyns, a new class of small molecule inhibitors of dynamin gtpase activity
Robertson, Mark J.,Hadzic, Gordana,Ambrus, Joseph,Pome, D. Yuri,Hyde, Emily,Whiting, Ainslie,Mariana, Anna,Von Kleist, Lisa,Chau, Ngoc,Haucke, Volker,Robinson, Phillip J.,McCluskey, Adam
supporting information; experimental part, p. 352 - 356 (2012/06/30)
Six focused rhodanine-based libraries, 60 compounds in total, were synthesized and evaluated as potential dynamin I GTPase inhibitors. Twenty-six were more potent than the lead compound with 13 returning IC50 values ≤10 μM, making the Rhodadyn
